Product overview
Tromethamine (Tris), also known as tris(hydroxymethyl)aminomethane, is a water-soluble cosmetic ingredient with the INCI name TROMETHAMINE and molecular formula C4H11NO3. It functions as a pH adjuster and buffering agent in skincare formulations and can neutralize compatible acidic thickening polymers. The Cosmetic Grade specification requires an assay of ≥99.5% on a dried basis. The technical specifications below follow the product TDS.
| INCI Name | CAS Number | Molecular Formula | Grade |
|---|---|---|---|
| TROMETHAMINE | 77-86-1 | C4H11NO3 | Cosmetic Grade |
| Appearance | Assay (dried basis) | Melting Range | pH (5% aqueous solution) |
|---|---|---|---|
| White Crystalline Powder | ≥99.5% | 168–172°C | 10.0–11.5 |
| Solution Appearance (5% aqueous) | Loss on Drying | Absorbance (290 nm, 40% aqueous) | Identification (IR) |
| Passes Test | ≤0.2% | ≤0.2 a.u. | Passes Test |
| Related Substances | Chloride | Residue on Ignition / Sulfated Ash | Iron (Fe) |
| Passes Test | ≤3 ppm | ≤0.05% | ≤1 ppm |
| Nickel (Ni) | Heavy Metals (as Pb) | Secondary Amines | Nitrosamines |
| ≤15 ppm | ≤5 ppm | ≤0.5% | ≤50 ppb |
Application guide
For cosmetic pH adjustment, buffering and pH control in skincare formulations, including creams, lotions and gels. Tromethamine can be evaluated as a neutralizer for compatible acidic thickening polymers.
Determine the addition level from the target pH, acid content and polymer requirements of the specific formulation; no universal dosage is specified. Do not use with nitrosating systems; avoid formation of nitrosamines.
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